Treatments grounded in collagen science — not cosmetic trends. We stimulate your skin’s natural repair processes instead of simply masking them.
Barnsley & London · Clinically led by Alan Apolakiatis RN
Skin ageing is fundamentally a biological process. Over time, collagen production slows, elastin weakens, and hyaluronic acid levels decline. Fibroblasts — the cells responsible for maintaining skin structure — become less active, leading to visible changes such as fine lines, laxity, dehydration, dullness, and loss of firmness.
At Restart Medical & Aesthetics Clinic, our approach focuses on regenerative medicine rather than temporary cosmetic masking. Instead of simply filling or freezing, we prioritise treatments that stimulate the skin’s own repair and collagen-building processes. Every protocol is designed to support natural skin biology through evidence-based, clinically led treatment plans tailored to the individual.
Type I collagen production declines roughly 1% per year from the mid-twenties. Compound that with falling hyaluronic acid and the gradual shortening of elastin — and you have the structural recipe for visible ageing. Regenerative treatments work because they stimulate the same fibroblast cells that built your skin in the first place.
Most signs of facial ageing are driven by three core biological changes. A good rejuvenation plan addresses all three.
Collagen production decreases gradually from the mid-twenties onward, while elastin continues to degrade with age. The result is reduced firmness, elasticity, and structural support.
Natural hyaluronic acid levels decline over time, causing skin to appear thinner, drier, and less resilient. Even before lines etch in, dehydrated skin reads as ageing skin.
Repeated facial expressions eventually create static lines that remain visible even at rest, particularly around the forehead, eyes, and mouth.
At Restart Medical, treatments are delivered with a medical-first mindset. Every plan is shaped around your individual skin biology — not a template.
Treatments are delivered or supervised by Alan Apolakiatis RN, with advanced training in facial aesthetics and regenerative medicine.
Every patient receives a structured medical history, photographic record, skin analysis, and discussion of goals against realistic outcomes.
Treatment plans are sequenced over 4–8 weeks. Single-session “fixes” are usually less effective than a properly paced course.
Strict clinical hygiene, sharps handling, consent and post-treatment review aligned with UK Care Quality Commission protocols.
Consultations focus on natural-looking, sustainable results. If a treatment isn’t clinically appropriate, we say so honestly.
Discreet appointments in Barnsley (Hawthorne Avenue, S71) and London.
Effective rejuvenation rarely relies on one treatment alone. The best outcomes come from layered protocols addressing skin quality, hydration, collagen stimulation, and muscle activity together.
Botulinum Toxin Type A
Anti-wrinkle treatments use Botulinum Toxin Type A to temporarily relax targeted facial muscles responsible for dynamic lines. The aim is always controlled softening — never an over-frozen appearance.
Common treatment areasProfhilo® Bio-Remodelling
A patented thermally cross-linked hyaluronic acid that stimulates fibroblast activity and promotes collagen and elastin synthesis through bio-remodelling at defined BAP-9 injection points. Improves skin quality without adding volume.
Common areasSalmon-Derived DNA Fragments
Highly purified DNA fragments that activate fibroblasts and upregulate type I collagen synthesis while exerting anti-inflammatory and free-radical-scavenging effects. Particularly effective for periorbital and crepey skin.
Especially effective forAutologous Growth Factors
An autologous blood product. A small venous draw is centrifuged in clinic to isolate platelet concentrate, then reintroduced via intradermal microinjection — releasing PDGF, TGF-β and VEGF growth factors. Drug-free and hypoallergenic by definition.
Commonly used forSunekos · Jalupro · Restylane Vital
Lightweight hyaluronic acid microinjections, often combined with amino acids and peptides. Address dehydration, fine lines and overall skin quality without altering facial structure or volume.
They helpVitamins · Antioxidants · Peptides
Microinjections of a tailored cocktail of vitamins, antioxidants, amino acids and peptides into the dermis. Frequently used as adjunctive therapy alongside Profhilo, polynucleotides or PRP for accelerated recovery and overall skin health.
SupportsA side-by-side view of the regenerative options. Plans are usually layered — not chosen in isolation.
| Treatment | Main Benefit | Sessions | Approx. Duration |
|---|---|---|---|
| Anti-Wrinkle Injections | Muscle relaxation | 1 | 3–4 months |
| Profhilo | Collagen stimulation & hydration | 2 | 6–9 months |
| Polynucleotides | Cellular repair & rejuvenation | 3 | 6–12 months |
| PRP | Growth-factor stimulation | 3 | 9–12 months |
| Skin Boosters | Deep hydration | 2–3 | 4–6 months |
The first appointment lasts around 30 minutes and is structured rather than rushed. There is never pressure to proceed on the day.
Conditions, medications, allergies, prior aesthetic treatments and any current dermatological issues.
Assessment of laxity, hydration, pigmentation, fine-line distribution and dynamic versus static creasing.
Standardised images for tracking progress — kept confidential and used only for clinical reference.
What you want to change, what’s achievable, and what’s better addressed via a different route.
An itemised treatment plan with sequencing, costs and review points. Transparent pricing throughout.
If a treatment isn’t clinically appropriate — or doing nothing is the right answer — we’ll say so.
Patient safety is central to every treatment plan. Adverse events are usually limited to local effects that resolve within 24–72 hours.
Dermal fillers restore volume and contour. Regenerative treatments such as Profhilo, PRP, and polynucleotides improve skin quality by stimulating natural repair processes. They sit alongside each other in a treatment plan rather than being interchangeable.
Anti-wrinkle injections work relatively quickly — visible from day five, peak at two weeks. Regenerative treatments develop more gradually over several weeks as collagen remodelling occurs.
Yes. These treatments are designed to improve skin quality subtly and progressively rather than dramatically changing facial appearance. The aim is “you, but rested” — not a different face.
PRP uses your own blood, making it naturally biocompatible and low-risk when performed clinically. Because the platelets are autologous, allergic reactions to the product itself are not possible.
Maintenance helps preserve results, but stopping treatment will not worsen your skin beyond its natural ageing process. Your skin returns to its untreated trajectory — it doesn’t decline faster than it would have otherwise.
Yes. Many patients combine anti-wrinkle injections with regenerative treatments for more comprehensive results. Layered protocols typically outperform single-treatment approaches.
Prices are set per treatment and per area. Plans are individualised. Anti-wrinkle injections start in the low hundreds; Profhilo, polynucleotide and PRP courses sit higher because they’re delivered across multiple sessions. An itemised quote is provided at consultation.
Call 07506 689894, email info@restartmedical.co.uk, or use the contact page. Initial consultations are usually available within a week.
If you’re considering regenerative aesthetics and want medically led, evidence-based advice — book a consultation with Restart Medical & Aesthetics Clinic. Initial assessments are unhurried and never high-pressure.
Submit your details and a member of our clinical team will respond to arrange a confidential consultation.
Prefer to talk? Call 07506 689894
Medical Policy & Disclaimer: The content on this page is for informational purposes only and does not constitute a medical offer. Anti-ageing and regenerative aesthetic treatments are elective, non-surgical procedures. Results vary by individual and are not guaranteed. Suitability must be assessed by a qualified clinician during consultation. Restart Medical creates a bespoke treatment plan for every patient; not all applicants will be suitable for treatment. Restart Medical & Aesthetics Clinic operates in line with UK ASA/CAP advertising standards and CQC-aligned clinical hygiene and consent protocols.